Let's Talk Dirty: The Hazards of Clean Living

e coli scupture,  Luke Jerram

    Think twice the next time you reach for the antibacterial wipes.  You might not be doing yourself any favors. In our attempts to achieve an increasing sterile world, we may be wiping out the beneficial bugs along with the bad guys. 

    This month's Utne Reader (new tag line:  Cure Ignorance) ran biologist Rob Dunn's Conservation article about "why cleanliness might be making us sick".   It's one of dozens of recent pieces discussing the hygiene hypothesis, linking decreases in diversity in the human microbiome to ever increasing rates of autoimmune illnesses, from mildly annoying to life threatening.  Think allergies, eczema, Crohn's disease, juvenile arthritis, Grave's-- maybe even MS.
    In autoimmune diseases, the body launches an attack on itself.  There's increasing support that these over-reactions are linked to some bad early training.  To attack an invader, you have to first identify it. To  identify, you have to be exposed to it, usually several times.  Theorists wonder if the lack of early exposure prevents the immature immune system from properly keying out the villains.
     Evidence is growing.  Science published a study in March that found that mice exposed to microbes early in their development kept their invariant natural killer T cells in check. Germ-free mice had  high levels of inkT cells in their lungs and were much more prone to inflammatory diseases.  These specially bred and raised mice aren't new to the experimental scene.  A study published in 2011 linked their lack of normal gut bacteria to changes in brain development and behavior.
    It's too early to know how directly this translates to humans.  But there's something going on.  We know this:  babies raised with pets tend to have fewer colds and ear infections.  Pets aren't quite as OCD as people.  They have no problem walking around for hours in the dirt, or eating what's on the floor, in the yard or crawling with vermin.  And they're unlikely to wash their paws or maws before they greet you.  This early exposure to the dirty world seems beneficial to babies.

SARS viral lace, by artist Laura Splann

   If a birth goes well, baby has already met a boatload of microbes on the journey.  Studies show that babies born vaginally get a large dose of beneficial bacteria missing from those delivered via cesarean section.  There's reported negative health links (increases in juvenile diabetes for the c-section delivered, for one) but it's not clear from studies I've found whether the poor gut colonization in early infancy is from the lack of exposure to mom's microflora or the common antibiotic medicating that usually accompanies a difficult birth and surgical delivery.
   Our bodies have ten times the number of microbial (virus, bacteria, etc) cells as human cells. Their genes outnumber us 360 to 1.  The microbiome in our gut is especially vital.  By now, even the least geeky of us is familiar with the term "probiotics"-- beneficial bacteria that colonize our gut and aid in everything from vitamin absorption and food digestion to fighting inflammation.  It's not unusual for MDs to recommend probiotics (whether in pill form or just a good cup of Nancy's yogurt) to patients on antibiotics.  That's because antibiotics are efficient little killers, but not very discriminating-- they mow down most everything in their path.  Wired magazine had a great infographic showing that for one particular species of beneficial bacteria, populations remained low even two years after a single 7 day treatment with clindamycin (for 9 months, the only remaining Bacteroides species was one particular clindamycin resistant strain). 
   Antibacterial soaps, lotions, tissues, wipes.  Antimicrobial gloves and sneakers, even underwear.  Sneezing into elbows, fistbumping instead of handshaking.  You'd think we'd all be healthier.  But the CDC reports that C-difficile infections are at an all time high.  C-diff is found normally, and benignly, in most of us, kept in check by the beneficial bacteria in our gut.  When that's out of whack,  C-diff can go wild, with potentially lethal results.  Those recently or currently on antibiotics are at the greatest risk.
    It's not just the little guys that are beneficial.  There's renewed interest and many recent investigations into the role of parasites in helping human immune systems.  Men's Health ran a lengthy article about treating ulcerative colitis and Crohns with (ok, ick) intestinal worms. 

gettin' dirty

     I'm not going that far.  And I'll probably continue to avoid a hug or handshake from someone with a cold or the flu.  But I'm feeling pretty good about eating unwashed organics fresh from the garden, playing in the dirt and using those cotton grocery bags.  And hey, mind if I have a sip of your drink?

For more on the microbiome, click the links above or check out these articles:
http://www.npr.org/blogs/health/2012/06/13/154913334/finally-a-map-of-all-the-microbes-on-your-body
http://www.nature.com/nature/focus/humanmicrobiota/index.htmlhttp://www.manchestersciencefestival.com/media/2009/Resources/Manchester_Science_Festival_-_Microbe_knitting_patterns.pdf



   

Be My Valentine

Rerun but worth a re-read even if you saw it the first time.  

Corvallis's First Alternative co-operative's a great place to fall in love with healthy eating, local foods and community sustainability.  They also publish a monthly newsletter, where I read this wonderful column by staffer Dave Williams.  He agreed I could reprint it here for those of you who don't get The Thymes.  Although it's aimed at singles, there's great advice for all of us this Valentine's day:

It’s once again time for the holiday that so many people seem to loathe.  Whether you’re lonely, just had a breakup, allergic to chocolate (I’m so sorry for you), or despise sappy movies, just remember: you define how you celebrate your holidays… and not just your holidays, but all of your days in general. You’re writing your own calendar here, folks, so if you don’t like a tradition or ritual, create your own and enjoy every moment of it!

I’m going through some huge transitions in my own personal life, but have decided to embrace the positive. I’m striving to show my gratitude and appreciation to all of the lovely, lovely souls I like to keep so close to me as opposed to closing myself off from them. This goes for all of my relationships and not just my love life. I am attempting to keep an open heart and mind this year, and I feel it necessary to show my love and excitement for my friends and family this Valentine’s more than to potential romances. I say, for those of us who are single, let’s send “Pal-entines” and appreciate the many, many wonderful people in our lives who make us smile. Let’s embrace our future with these people and learn to laugh and enjoy even the sappiest of holidays together rather than dreading them, or feeling any sort of inadequacy. We are all bright entities. If you are single, then I want you to take a moment to feel completely empowered.  Feel your inner, personal strength and energy that is completely unique to your spirit, and your spirit alone.  Send yourself a love letter. Learn to love yourself in new and unexpected ways, for previously undiscovered reasons, and then do the same for your closest friends or family members. Send postcards. Send small, homemade gifts. Make everyone you know a mix CD and let them hear the music that keeps you dancing throughout the day… the music that touches and moves you. Love everyone, including your ex-partners and antagonists. Transform your negative relationships into positive and ongoing experiences. Don’t be so hard on yourself. Do your best. Keep everyone, absolutely everyone, close to your heart. If we do this together, we will truly feel love on even the most seemingly isolating holidays of the year.

Love life.

Dave Williams,

Outreach Assistant

(reprinted with permission from the Feb edition, first Alternative Thymes)